教育经历
1.2000.9至2003.6,四川大学华西公共卫生学院,流行病与卫生统计,博士生
2.1997.9至2000.6,福建师范大学数学系,概率论与数理统计,硕士生
3.1993.9至1997.6,福建师范大学数学系,数学教育,本科生
科研与学术经历
1.2008.5-至今,东南大学,流行病与卫生统计,副教授,硕士生导师
2.2003.7-2008.4,东南大学,流行病与卫生统计,讲师
研究方向
1.机器学习方法在医学领域中的应用
2.纵向数据的统计分析方法
3.临床试验的统计分析
主持或参加科研项目(课题)情况
1. 国家自然科学基金面上项目. 诊断分类模型在中医证候量化及临床诊断的应用研究.2013-01至2016-12, 主持.
2. 国家自然科学基金青年项目. 潜在变量模型在中医证候量化中的应用研究. 2007-01至2009-12, 主持.
3. 国家自然科学基金重点项目.基于磁共振新技术及多组学的胰腺癌生境图谱研究. 2024-01至2028-12,参与。
代表性研究成果和学术奖励情况
代表性研究成果:
1.Wu XM, Qian YK, Chen HL, Hu CH, Chen BW*. Efficacy and Safety of Anti-HER2 Targeted Therapy for Metastatic HR-Positive and HER2-Positive Breast Cancer: A Bayesian Network Meta-Analysis. Curr Oncol. 2023,30(9):8444-8463. doi: 10.3390/curroncol30090615
2.Chen B, Jiao Z, Shen T, Fan R, Chen Y, Xu Z. Early antidepressant treatment response prediction in major depression using clinical and TPH2 DNA methylation features based on machine learning approaches. BMC Psychiatry. 2023, 23(1):299. doi:10.1186/s12888-023-04791-z
3. Zang YT, Xu BY, Chen SZ, Mutale G, Cao QY*, Chen BW*. The Relationship between Mental Disorders and Personality of Outpatients in a Psychiatric Clinic in Nanjing, China. International Journal of Mental Health Promotion,2023, DOI: 10.32604/ijmhp.2023.042584
4 Zhao M, Qiu S, Wu X, Miao P, Jiang Z, Zhu T, Xu X, Zhu Y, Zhang B, Yuan D, Zhang Y, Sun W, He A, Zhao M, Hou W, Zhang Y, Shao Z, Jia M, Li M, Chen J, Xu J, Chen B*, Zhou Y*, Shen Y*. Efficacy and Safety of Niraparib as First-Line Maintenance Treatment for Patients with Advanced Ovarian Cancer: Real-World Data from a Multicenter Study in China. Target Oncol. 2023,. doi: 10.1007/s11523-023-00999-x
5. Hong X, Qiu S, Wu X, Chen S, Chen X, Zhang B, He A, Xu Y, Wang J, Gao Y, Xu X, Sun L, Zhang Y, Xiang L, Zhou J, Guan Q, Zhu Y, Liu H, Xu H, Zhou Y, Chen B*, Shen Y*. Efficacy and Safety of Anlotinib in Overall and Disease-Specific Advanced Gynecological Cancer: A Real-World Study. Drug Des Devel Ther. 2023,17:2025-2033. doi: 10.2147/DDDT.S408304
6. Chen S, Zang Y, Xu B, Lu B, Ma R, Miao P, Chen B*. An Unsupervised Deep Learning-Based Model Using Multiomics Data to Predict Prognosis of Patients with Stomach Adenocarcinoma. Comput Math Methods Med. 2022,2022:5844846. doi: 10.1155/2022/5844846
7. Li T, Qi R, Zhou YH, Luo Y, Wang SY, Chen B*, Xu B*. Attitudes and Factors Associated With Intention to the Third Dose of COVID-19 Vaccine Among Adolescents: A Cross-Sectional Survey in 3 Provinces of China. Disaster Med Public Health Prep. 2022 ,17:e201. doi: 10.1017/dmp.2022.181
8. Fan R, Hua T, Shen T, Jiao Z, Yue Q, Chen B*, Xu Z*. Identifying patients with major depressive disorder based on tryptophan hydroxylase-2 methylation using machine learning algorithms. Psychiatry Res. 2021,306:114258. doi: 10.1016/j.psychres.2021.114258
9.马溶基,焦志刚,缪鹏程,陆贝尔,陈华玲,钱永康,陈炳为*.基于基准实验的生存数据机器学习和COX模型的区分度性能比较.现代预防医学,2023,50(13):2344-2348.
10.凡如,许碧云,焦志刚,臧一腾,陈思臻,陈炳为*,周卫红*.基于极端梯度提升算法的高血压识别模型建立.中国卫生统计,2023,40(01):74-77.
11. 焦志刚,凡如,许碧云,陈思臻,臧一腾,王诗远,陈炳为*.临床纵向数据缺失的多重填补及其敏感性分析.中国临床药理学与治疗学,2021,26(09):1037-1041.
12.岳青青,焦志刚,凡如,臧一腾,王健力,陈炳为*.倾向性评分法简介及其SAS实现.中国卫生统计,2021,38(01):144-147.
学术奖励:
基于“3M”模式的中成药临床药理创新体系构建与应用. 2022, 中国中西医结合学会科学技术一等奖(排名第九).